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PMID: 2448635 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila.

Nature ·Vol. 331 ·No. 6152 ·1988-01-14 ·Pages 137-42

Schwarz TL, Tempel BL, Papazian DM, Jan YN, Jan LY

Abstract

At least four probable components of potassium channels are encoded at the Drosophila Shaker locus, by a family of alternatively spliced transcripts. Alternative splicing may provide one mechanism of generating the remarkable diversity of potassium channels.

MeSH Terms
Amino Acid Sequence Animals Base Sequence Chromosome Mapping Cloning, Molecular DNA/genetics DNA, Recombinant Drosophila melanogaster/genetics Ion Channels/physiology Molecular Sequence Data Mutation Potassium/metabolism Proteins/genetics RNA Splicing Transcription, Genetic
Chemicals
DNA, Recombinant Ion Channels Proteins DNA Potassium
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Schwarz T L
Howard Hughes Medical Institute, University of California, San Francisco 94143.
Tempel B L
Papazian D M
Jan Y N
Jan L Y
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/331137a0
Published
1988-01-14
Pages
137-42
Language
English
Region
England
NLM ID
0410462
Subset
IM
Corrections
ErratumIn
-
External Links
PubMed source DOI: 10.1038/331137a0 View journal details
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