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题目:
Biotransformation, a promising technology for anti-cancer drug development.
作者:
Gao(Fei),Zhang(Jin-Ming),Wang(Zhan-Guo),Peng(Wei),Hu(Hui-Ling),Fu(Chao-Mei)
状态:
发布时间2013-12-02 , 更新时间 2013-12-02
期刊:
Asian Pac J Cancer Prev
摘要:
With the high morbidity and mortality caused by cancer, finding new and more effective anti-cancer drugs is very urgent. In current research, biotransformation plays a vital role in the research and development of cancer drugs and has obtained some achievements. In this review, we have summarized four applications as follows: to exploit novel anti-cancer drugs, to improve existing anti-cancer drugs, to broaden limited anti-cancer drug resources and to investigate correlative mechanisms. Three different groups of important anti-cancer compounds were assessed to clarify the current practical applications of biotransformation in the development of anti-cancer drugs.
语言:
eng
DOI:

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