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PMID: 24270525 Published · ppublish English Journal Article

Effects of marked chromosome sections on quantitative traits in the mouse.

Kluge R, Geldermann H

Abstract

An investigation of the influences of marked chromosome sections on quantitative traits in a backcross-generation with 2321 mice (C57BL/6JHan × (AKR/NHan×C57BL/6JHan)) is described. In the animals the chromosomes 1, 4, 7, and 8 were marked by the gene loci Idh-1, Gpd-1, Gpi-1s, Es-1, resp. Within the backcross-generation, for Idh-1 and Es-1, more heterozygous genotypes were found than expected under random conditions. By comparing animal-groups with different homologous sections of the marked chromosomes, effects were observed on quantitative traits (body length and weight, dry weight and matter, fat weight and content). The results indicate that a few chromosome sections influence to a major extent the genetic variation of some quantitative traits.

Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kluge R
Zentralinstitut für Versuchstiere, Hanover, Federal Republic of Germany.
Geldermann H
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13 references, click to expand
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Article Info
Journal
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik
Abbr.
Theor Appl Genet
ISSN
0040-5752
Published
1982-03-00
Pages
1-4
Language
English
Region
Germany
NLM ID
0145600
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