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PMID: 2426783 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Ion channels in yeast.

Science (New York, N.Y.) ·Vol. 233 ·No. 4769 ·1986-09-12 ·Pages 1195-7

Gustin MC, Martinac B, Saimi Y, Culbertson MR, Kung C

Abstract

Voltage-dependent ion channels have been found in the plasma membrane of the yeast Saccharomyces cerevisiae. Ion channel activities were recorded from spheroplasts or patches of plasma membrane with the patch-clamp technique. The most prominent activities came from a set of potassium channels with the properties of activation by positive but not negative voltages, high selectivity for potassium over sodium ion, unit conductance of 20 picosiemens, inhibition by tetraethylammonium or barium ions, and bursting kinetics.

MeSH Terms
Cell Membrane/physiology Electrophysiology Ion Channels/physiology Membrane Potentials Potassium/metabolism Saccharomyces cerevisiae/physiology Sodium/metabolism
Chemicals
Ion Channels Sodium Potassium
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Gustin M C
Martinac B
Saimi Y
Culbertson M R
Kung C
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1986-09-12
Pages
1195-7
Language
English
Region
United States
NLM ID
0404511
Subset
IM
Grants
NIGMS NIH HHS · GM-22714 · United States
NIGMS NIH HHS · GM-26217 · United States
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