Characterization of the in vitro effects of glucocorticosteroids on NK cell activity.
作者:
Pedersen(B K),Beyer(J M)
状态:
发布时间1986-07-03
, 更新时间 2013-11-21
期刊:
Allergy
摘要:
The NK cell activity of mononuclear cells as well as monocyte-depleted, Percoll-fractionated, NK cell-enriched effector cells against K 562 target cells was inhibited by methylprednisolone (MP) and hydrocortisone (HC) in a dose-dependent manner. The effector/target cell conjugate formation was studied in a single cell agarose assay, and it was shown that MP and HC partly inhibited the NK cell activity by inhibition of the adhesion of effector cells to target.