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PMID: 2420682 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Molecular mapping of the rosy locus in Drosophila melanogaster.

Genetics ·Vol. 112 ·No. 4 ·1986-04-00 ·Pages 769-83

Coté B, Bender W, Curtis D, Chovnick A

Abstract

The DNA from the chromosomal region of the Drosophila rosy locus has been examined in 83 rosy mutant strains. Several spontaneous and radiation-induced alleles were associated with insertions and deletions, respectively. The lesions are clustered in a 4-kb region. Some of the alleles identified on the DNA map have been located on the genetic map by fine-structure recombination experiments. The genetic and molecular maps are collinear, and the alignment identifies the DNA location of the rosy control region. A rosy RNA of 4.5 kb has been identified; its 5' end lies in or near the control region.

MeSH Terms
Animals Chromosome Mapping Cloning, Molecular DNA/genetics DNA Restriction Enzymes Drosophila melanogaster/genetics,radiation effects Mutagens Mutation RNA/genetics
Chemicals
Mutagens RNA DNA DNA Restriction Enzymes
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Coté B
Bender W
Curtis D
Chovnick A
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Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
Published
1986-04-00
Pages
769-83
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1202776
Subset
IM
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