Home LiteratureArticle Details
PMID: 2416398 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Loose patch clamp recording of ionic currents in demyelinated frog nerve fibers.

Brain research ·Vol. 359 ·No. 1-2 ·1985-12-16 ·Pages 338-42

Chiu SY, Shrager P, Ritchie JM

Abstract

Ionic currents in demyelinated segments of frog sciatic nerves have been detected by means of a patch clamp technique. Axons were examined 6-13 days after lysolecithin-induced demyelination. Both voltage-gated sodium channels and voltage-gated potassium channels could be demonstrated in the demyelinated axolemma.

MeSH Terms
Animals Demyelinating Diseases/physiopathology Ion Channels/metabolism Peripheral Nerves/physiopathology Potassium/metabolism Rana catesbeiana Sodium/metabolism
Chemicals
Ion Channels Sodium Potassium
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Chiu S Y
Shrager P
Ritchie J M
Article Info
Journal
Brain research
Abbr.
Brain Res
ISSN
0006-8993
DOI
10.1016/0006-8993(85)91446-5
Published
1985-12-16
Pages
338-42
Language
English
Region
Netherlands
NLM ID
0045503
Subset
IM
Grants
NINDS NIH HHS · NS 08304 · United States
NINDS NIH HHS · NS 12327 · United States
NINDS NIH HHS · NS 17965 · United States
External Links
PubMed source DOI: 10.1016/0006-8993(85)91446-5 View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2