Home LiteratureArticle Details

PMID: 2415826 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Role of acetylcholine receptor subunits in gating of the channel.

Nature ·Vol. 318 ·No. 6046 ·1985-00-00 ·Pages 538-43

Sakmann B, Methfessel C, Mishina M, Takahashi T, Takai T, Kurasaki M, Fukuda K, Numa S

Abstract

The Torpedo and calf acetylcholine receptors and hybrids composed of subunits from the two species have been produced in Xenopus oocytes by the use of the cloned complementary DNAs. Single-channel current measurements indicate that these receptors form channels of similar conductance but with different gating behaviour.

MeSH Terms

Animals Cattle Electric Conductivity Ion Channels/physiology Macromolecular Substances Oocytes Receptors, Nicotinic/physiology Structure-Activity Relationship Torpedo Xenopus

Chemicals

Ion Channels Macromolecular Substances Receptors, Nicotinic

Authors & Affiliations

8 authors, click to expand affiliations / ORCID

Sakmann B

Methfessel C

Mishina M

Takahashi T

Takai T

Kurasaki M

Fukuda K

Numa S

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/318538a0

Published

1985-00-00

Pages

538-43

Language

English

Region

England

NLM ID

0410462

Subset

External Links

PubMed source DOI: 10.1038/318538a0 View journal details

Analysis Services

Role of acetylcholine receptor subunits in gating of the channel.

Contact

WeChat Official Account