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题目:: Functions, aberrations, and advances for chromatin modulation in cancer.
作者:: Conte(Mariarosaria),Altucci(Lucia)
状态:: 发布时间2013-10-11 , 更新时间 2013-10-11
期刊:: Cancer Treat Res
摘要:: Cancer initiation and progression is causally connected to genome and epigenome deregulations. Epigenetic deregulations (such as DNA methylation, histone modifications, and miRNA-based modulation) have been increasingly reported in tumorigenesis and different chromatin-modulating enzymes have been discovered and classified and their aberrations connected to cancer. A better insight into alterations occurring on chromatin enzymes and their impact in cancer thus represents a crucial step in exploiting epigenetic targeting in cancer prevention and treatment.
语言:: eng
DOI:: 10.1007/978-3-642-38007-5_13

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