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PMID: 2410329 Published · ppublish English Case Reports Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Elevation of serum CA 125 prior to diagnosis of an epithelial ovarian carcinoma.

Gynecologic oncology ·Vol. 22 ·No. 1 ·1985-09-00 ·Pages 115-20

Bast RC, Siegal FP, Runowicz C, Klug TL, Zurawski VR, Schonholz D, Cohen CJ, Knapp RC

Abstract

In a single fortuitous case it has been possible to measure serum levels of CA 125 during 3 years preceding the diagnosis of an epithelial ovarian carcinoma. CA 125 levels were elevated 10-12 months prior to clinical detection of the malignancy. CA 125 deserves further evaluation as a marker for early detection of ovarian cancer.

MeSH Terms

Agammaglobulinemia/immunology Antigens, Neoplasm/analysis Antigens, Tumor-Associated, Carbohydrate Epitopes/analysis Female Humans Middle Aged Ovarian Neoplasms/immunology Time Factors

Chemicals

Antigens, Neoplasm Antigens, Tumor-Associated, Carbohydrate Epitopes

Authors & Affiliations

8 authors, click to expand affiliations / ORCID

Bast R C

Siegal F P

Runowicz C

Klug T L

Zurawski V R

Schonholz D

Cohen C J

Knapp R C

Article Info

Journal

Gynecologic oncology

Abbr.

Gynecol Oncol

ISSN

0090-8258

DOI

10.1016/0090-8258(85)90015-0

Published

1985-09-00

Pages

115-20

Language

English

Region

United States

NLM ID

0365304

Subset

Grants

NIAID NIH HHS · AI 16186 · United States

NCRR NIH HHS · RR-00071 · United States

External Links

PubMed source DOI: 10.1016/0090-8258(85)90015-0 View journal details

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Elevation of serum CA 125 prior to diagnosis of an epithelial ovarian carcinoma.

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