A foot in the door: how the chromatin modifier Brg1 and Pax6 jointly potentiate adult neurogenesis.
作者:
Jaglin(Xavier H),Fishell(Gord)
状态:
发布时间2013-10-07
, 更新时间 2016-11-25
期刊:
Cell Stem Cell
摘要:
Transcription factors and chromatin modifiers are known to contribute to cell specification. However, whether and how they jointly act is poorly understood. In this issue of Cell Stem Cell, Ninkovic et al. show that Pax6 and Brg1 cooperate to modulate gene expression in order to direct neurogenic fate in the olfactory bulb.