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题目:: Insights into the role of cell-cell junctions in physiology and disease.
作者:: Wei(Qi),Huang(Hayden)
状态:: 发布时间2013-09-10 , 更新时间 2016-05-18
期刊:: Int Rev Cell Mol Biol
摘要:: Contacting cells establish different classes of intricate structures at the cell-cell junctions. These structures are of increasing research interest as they regulate a broad variety of processes in development and disease. Further, in vitro studies are revealing that various cell-cell interaction proteins are involved not only in cell-cell processes but also in many additional aspects of physiology, such as migration and apoptosis. This chapter reviews the basic classification of cell-cell junctional structures and some of their representative proteins. Their roles in development and disease are briefly outlined, followed by a section on contemporary methods for probing cell-cell interactions and some recent developments. This chapter concludes with a few suggestions for potential research directions to further develop this promising area of study.
语言:: eng
DOI:: 10.1016/B978-0-12-407694-5.00005-5

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