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PMID: 23929338 Published · ppublish English Letter Research Support, Non-U.S. Gov't

Targeted genome modification of crop plants using a CRISPR-Cas system.

Nature biotechnology ·Vol. 31 ·No. 8 ·2013-08-00 ·Pages 686-8

Shan Q, Wang Y, Li J, Zhang Y, Chen K, Liang Z, Zhang K, Liu J, Xi JJ, Qiu JL, Gao C

Abstract

暂无摘要

MeSH Terms
Bacterial Proteins/genetics Base Sequence CRISPR-Associated Protein 9 CRISPR-Associated Proteins/genetics CRISPR-Cas Systems/genetics Crops, Agricultural/genetics DNA Endonucleases/genetics Gene Editing/methods Gene Targeting/methods Genome, Plant Inverted Repeat Sequences Oryza/genetics Protoplasts/metabolism Triticum/genetics
Chemicals
Bacterial Proteins CRISPR-Associated Proteins DNA CRISPR-Associated Protein 9 Cas9 endonuclease Streptococcus pyogenes Endonucleases
Authors & Affiliations
11 authors, click to expand affiliations / ORCID
Shan Qiwei
Wang Yanpeng
Li Jun
Zhang Yi
Chen Kunling
Liang Zhen
Zhang Kang
Liu Jinxing
Xi Jianzhong Jeff
Qiu Jin-Long
Gao Caixia
References (12)
12 references, click to expand
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    Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):12028-33 PMID: 20508152
  9. RNA-guided editing of bacterial genomes using CRISPR-Cas systems.
    Nat Biotechnol. 2013 Mar;31(3):233-9 PMID: 23360965
  10. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering.
    Cell. 2013 May 9;153(4):910-8 PMID: 23643243
  11. Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria.
    Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):E2579-86 PMID: 22949671
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Article Info
Journal
Nature biotechnology
Abbr.
Nat Biotechnol
ISSN
1546-1696
DOI
10.1038/nbt.2650
Published
2013-08-00
Pages
686-8
Language
English
Region
United States
NLM ID
9604648
Subset
IM
External Links
PubMed source DOI: 10.1038/nbt.2650 View journal details
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