Statistical mechanics of pluripotency.

Cell ·第 154 卷 ·第 3 期 ·2013-10-28

MacArthur(Ben D),Lemischka(Ihor R)

摘要

Recent reports using single-cell profiling have indicated a remarkably dynamic view of pluripotent stem cell identity. Here, we argue that the pluripotent state is not well defined at the single-cell level but rather is a statistical property of stem cell populations, amenable to analysis using the tools of statistical mechanics and information theory.

文献信息

期刊

Cell

期刊简称

Cell

ISSN

0092-8674

DOI

10.1016/j.cell.2013.07.024

发表日期

2013-10-28

收录日期

2013-08-05

更新日期

2013-08-05

语言

英语

国家/地区

United States

NLM ID

0413066

外部链接

PubMed 原文 DOI: 10.1016/j.cell.2013.07.024 查看期刊详情

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Statistical mechanics of pluripotency.

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