Mycophenolic acid morpholinoethylester (RS-61443) is a new immunosuppressant that prevents and halts heart allograft rejection by selective inhibition of T- and B-cell purine synthesis.

Transplantation proceedings ·Vol. 22 ·No. 4 ·1990-08-00 ·Pages 1659-62

Morris RE, Hoyt EG, Murphy MP, Eugui EM, Allison AC

Abstract

暂无摘要

MeSH Terms

Animals B-Lymphocytes/drug effects,immunology,metabolism Cyclosporins/therapeutic use Drug Therapy, Combination Graft Rejection Graft Survival Heart Transplantation/immunology Immunosuppressive Agents/therapeutic use Male Mice Mice, Inbred BALB C Mice, Inbred C3H Mycophenolic Acid/analogs & derivatives,therapeutic use Purines/antagonists & inhibitors,metabolism T-Lymphocytes/drug effects,immunology,metabolism Transplantation, Heterotopic Transplantation, Homologous

Chemicals

Cyclosporins Immunosuppressive Agents Purines Mycophenolic Acid

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Morris R E

Department of Cardiovascular Surgery, Stanford University School of Medicine, CA 94305-5247.

Hoyt E G

Murphy M P

Eugui E M

Allison A C

Article Info

Journal

Transplantation proceedings

Abbr.

Transplant Proc

ISSN

0041-1345

Published

1990-08-00

Pages

1659-62

Language

English

Region

United States

NLM ID

0243532

Subset

External Links

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Mycophenolic acid morpholinoethylester (RS-61443) is a new immunosuppressant that prevents and halts heart allograft rejection by selective inhibition of T- and B-cell purine synthesis.

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