| GeneLibs

题目:: The B1-cell subpopulation is diminished in patients with relapsing-remitting multiple sclerosis.
作者:: Tørring(Caroline),Petersen(Charlotte Christie),Bjerg(Lasse),Kofod-Olsen(Emil),Petersen(Thor),Höllsberg(Per)
状态:: 发布时间2013-09-09 , 更新时间 2013-09-09
期刊:: J Neuroimmunol
摘要:: B cell subsets in newly diagnosed untreated, relapsing-remitting multiple sclerosis (MS) patients were examined. The fraction of CD20(+) B cells was significantly increased in MS. Among subsets of B cells, MS patients had increased frequency of naïve cells, but reduced frequency of memory and B1 cells. The frequencies of B1 cells were inversely correlated with the time since last attack. B1 cells resembled the phenotype of either lymphocytes (CD11b(-) B1 cells) or monocytes (CD11b(+) B1 cells) and a small fraction of cells was CD3(+)CD20(+) by confocal microscopy.
语言:: eng
DOI:: 10.1016/j.jneuroim.2013.06.002

文献库文献相关信息