Oncogenic miRNAs and the perils of losing control of a stem cell's epigenetic identity.
作者:
Dalerba(Piero),Clarke(Michael F)
状态:
发布时间2013-07-05
, 更新时间 2016-05-18
期刊:
Cell Stem Cell
摘要:
Pathways that regulate epigenetic control of stem cell identity are critical to the molecular etiology of cancer. In back-to-back articles in Cell and Cell Stem Cell, Song et al. identify miR-22 as both a repressor of TET proteins and a powerful oncogene in the mammary epithelium and hematopoietic system.