"License to kill" reflects joint action of CD4 and CD8 T cells.
作者:
Melief(Cornelis J M)
状态:
发布时间2013-08-15
, 更新时间 2016-11-25
期刊:
Clin Cancer Res
摘要:
The spontaneous T-cell responses to the KIF20A cancer-associated antigen found by Tomita and colleagues among peripheral blood mononuclear cells of patients with cancer, but not healthy people, involve both CD4 and CD8 T cells. Synthetic long peptides of KIF20A stimulate synergy between these two T-cell types to promote cancer cell killing.