Combination checkpoint blockade--taking melanoma immunotherapy to the next level.

Antibodies, Monoclonal/administration & dosage,therapeutic use Antibodies, Monoclonal, Humanized Antineoplastic Agents/administration & dosage Antineoplastic Combined Chemotherapy Protocols/therapeutic use CTLA-4 Antigen/antagonists & inhibitors Female Humans Ipilimumab Male Melanoma/drug therapy Nivolumab Programmed Cell Death 1 Receptor/antagonists & inhibitors Skin Neoplasms/drug therapy

Antibodies, Monoclonal Antibodies, Monoclonal, Humanized Antineoplastic Agents CTLA-4 Antigen Ipilimumab PDCD1 protein, human Programmed Cell Death 1 Receptor Nivolumab pembrolizumab