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PMID: 2369684 Published · ppublish English Case Reports Journal Article

Myasthenia gravis after allogeneic bone marrow transplantation: report of a new case and pathogenetic considerations.

Bone marrow transplantation ·Vol. 5 ·No. 6 ·1990-06-00 ·Pages 435-7

Grau JM, Casademont J, Monforte R, Marín P, Grañena A, Rozman C, Urbano-Márquez A

Abstract

A 21-year-old caucasian man with T acute lymphoblastic leukemia underwent a bone marrow transplantation (BMT) and developed classic myasthenia gravis (MG) 46 months later. The association of almost all published cases with HLA B35 is discussed, as are the clinical aspects suggesting that BMT survivors are at risk for developing MG as part of the spectrum of chronic graft-versus-host disease.

MeSH Terms
Adult Bone Marrow Transplantation/adverse effects Graft vs Host Disease/complications,etiology Humans Male Myasthenia Gravis/diagnosis,etiology,pathology Precursor Cell Lymphoblastic Leukemia-Lymphoma/surgery Transplantation, Homologous/adverse effects
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Grau J M
Muscle Research Unit, Hospital Clinic i Provincial, Barcelona, Spain.
Casademont J
Monforte R
Marín P
Grañena A
Rozman C
Urbano-Márquez A
Article Info
Journal
Bone marrow transplantation
Abbr.
Bone Marrow Transplant
ISSN
0268-3369
Published
1990-06-00
Pages
435-7
Language
English
Region
England
NLM ID
8702459
Subset
IM
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