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题目:: Modeling cell-in-cell structure into its biological significance.
作者:: He(M-f),Wang(S),Wang(Y),Wang(X-n)
状态:: 发布时间2013-05-17 , 更新时间 2015-04-26
期刊:: Cell Death Dis
摘要:: Although cell-in-cell structure was noted 100 years ago, the molecular mechanisms of 'entering' and the destination of cell-in-cell remain largely unclear. It takes place among the same type of cells (homotypic cell-in-cell) or different types of cells (heterotypic cell-in-cell). Cell-in-cell formation affects both effector cells and their host cells in multiple aspects, while cell-in-cell death is under more intensive investigation. Given that cell-in-cell has an important role in maintaining homeostasis, aberrant cell-in-cell process contributes to the etiopathology in humans. Indeed, cell-in-cell is observed in many pathological processes of human diseases. In this review, we intend to discuss the biological models of cell-in-cell structures under physiological and pathological status.
语言:: eng
DOI:

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