Chromoplexy: a new category of complex rearrangements in the cancer genome.
作者:
Shen(Michael M)
状态:
发布时间2013-05-17
, 更新时间 2016-10-25
期刊:
Cancer Cell
摘要:
Widespread structural alterations of cancer genomes are increasingly observed in a broad spectrum of tumors. In a recent issue of Cell, Baca and colleagues describe large chains of rearrangements that coordinately affect multiple chromosomes in prostate cancer. This phenomenon of chromoplexy may define cancer subtypes and drive punctuated tumor evolution.