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PMID: 23601100 Published · ppublish English Comment Journal Article

Taking sides: interferons in leprosy.

Cell host & microbe ·Vol. 13 ·No. 4 ·2013-04-17 ·Pages 377-8

Desvignes LP, Ernst JD

Abstract

In a recent Science paper, Teles et al. (2013) show that type I and II interferons (IFNs) are reciprocally expressed in the polar immune forms of leprosy, with type I IFNs inducing IL-10 that interferes with the antimycobacterial effects of type II IFNs (IFNγ) at the site of infection.

Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Desvignes Ludovic P
New York University School of Medicine, 522 First Avenue, Smilow 901, New York, NY 10016, USA.
Ernst Joel D
References (7)
7 references, click to expand
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Article Info
Journal
Cell host & microbe
Abbr.
Cell Host Microbe
ISSN
1934-6069
DOI
10.1016/j.chom.2013.04.001
Published
2013-04-17
Pages
377-8
Language
English
Region
United States
NLM ID
101302316
PMCID
PMC3671607
Grants
NIAID NIH HHS · R01 AI051242 · United States
NIAID NIH HHS · R01 AI084041 · United States
NIAID NIH HHS · R01 AI090928 · United States
Corrections
CommentOn
PMID: 23449998
External Links
PubMed source DOI: 10.1016/j.chom.2013.04.001 PMC Full Text View journal details
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