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题目:: Research status and prospect of stem cells in the treatment of diabetes mellitus.
作者:: Liu(Xiaofang),Wang(Yunfang),Li(Yali),Pei(Xuetao)
状态:: 发布时间2013-04-08 , 更新时间 2013-04-08
期刊:: Sci China Life Sci
摘要:: Beta cell mass and function are decreased to varying degrees in diabetes. Islet cell replacement or regenerative therapy may offer great therapeutic promise to people with diabetes. In addition to primary pancreatic β cells, recent studies on regeneration of functional insulin producing cells (IPCs) revealed that several alternative cell sources, including embryonic stem cells, induced pluripotent stem cells and adult stem cells, can generate IPCs by differentiation, reprogramming, and trans-differentiation. In this review, we discuss stem cells as a potential alternative cell source for the treatment of diabetes.
语言:: eng
DOI:: 10.1007/s11427-013-4469-1

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