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题目:: An inflammatory situation: SOX2 and STAT3 cooperate in squamous cell carcinoma initiation.
作者:: Bass(Adam J),Wang(Timothy C)
状态:: 发布时间2013-03-11 , 更新时间 2016-05-18
期刊:: Cell Stem Cell
摘要:: Although SOX2 has been identified as a squamous cell carcinoma oncogene, mechanisms of SOX2-induce oncogenesis have remained elusive. In this issue of Cell Stem Cell, Li et al. (2013) show that SOX2 synergizes with inflammation-induced STAT3 activation to transform basal progenitors and initiate squamous cell carcinoma.
语言:: eng
DOI:: 10.1016/j.stem.2013.02.004

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