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题目:: Association between allergies, asthma, and breast cancer risk among women in Ontario, Canada.
作者:: Lowcock(Elizabeth C),Cotterchio(Michelle),Ahmad(Noor)
状态:: 发布时间2013-04-22 , 更新时间 2015-11-19
期刊:: Cancer Causes Control
摘要:: To investigate the association between allergies, asthma, and breast cancer risk in a large, population-based case-control study.,Breast cancer cases (n = 3,101) were identified using the Ontario Cancer Registry and population controls (n = 3,471) through random digit dialing. Self-reported histories of allergies, hay fever, and asthma were collected by questionnaire. Logistic regression was used to assess associations between breast cancer risk and history of allergy/hay fever and asthma, with 16 possible confounders examined. Analyses were stratified by menopausal status.,A history of allergies or hay fever was associated with a small reduction in breast cancer risk [age-adjusted odds ratio (AOR) = 0.86, 95 % confidence interval (CI) 0.77-0.96] and did not differ by menopausal status. Asthma was not associated with breast cancer risk overall; however, among premenopausal women, asthma was associated with a reduced risk of breast cancer (AOR = 0.72, 95 % CI 0.54-0.97).,A history of allergies may be associated with a modest reduction in breast cancer risk. Asthma does not appear to be associated with breast cancer risk overall; however, asthma may be associated with reduced breast cancer risk among premenopausal women.
语言:: eng
DOI:: 10.1007/s10552-013-0177-1

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