Metabolic makeover for HSCs.

Cell stem cell ·Vol. 12 ·No. 1 ·2013-01-03 ·Pages 1-3

Warr MR, Passegué E

Abstract

Hematopoietic stem cells (HSCs) must at times exit quiescence to divide and produce differentiated blood cells. In this issue of Cell Stem Cell, Takubo et al. (2013) and Yu et al. (2013) show that these opposing actions require distinct metabolic programs to meet the changing energy demands of self-renewing HSCs.

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Warr Matthew R

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Department of Medicine, Hematology/Oncology Division, University of California at San Francisco, San Francisco, CA 94143, USA.

Passegué Emmanuelle

Article Info

Journal

Cell stem cell

Abbr.

Cell Stem Cell

ISSN

1875-9777

DOI

10.1016/j.stem.2012.12.005

Published

2013-01-03

Pages

1-3

Language

English

Region

United States

NLM ID

101311472

Grants

NHLBI NIH HHS · R01 HL111266 · United States

Corrections

CommentOn

PMID: 20804974

CommentOn

PMID: 23290137

External Links

PubMed source DOI: 10.1016/j.stem.2012.12.005 View journal details

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Metabolic makeover for HSCs.

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