This article describes a method of gastrographic examination and its use in diagnosis of gastric cancer. Gastrography includes four examination methods: barium filled, mucosal relief, compression, and double contrast studies. Diagnosis by gastrography is based on the histogenesis of gastric cancer. Depressive undifferentiated type cancer, which arises from the fundic gland mucosa, shows a clear depressed border between the carcinoma and normal mucosa. The surface of the cancer also shows granular changes in regenerative mucosa. Depressive differentiated type cancer, which develops from intestinal metaplastic mucosa, has a smooth mucosal surface and shows depression of the cancer accompanied with slightly elevated margins. Most elevated type gastric cancers are intramucosal cancers of differentiated type carcinoma. However, cancers showing elevation of more than 3cm would be predicted to show invasive potential by conventional statistical gastric cancer studies.