Treg cells acquire new directions, cytokines navigate.

Immunity ·Vol. 37 ·No. 3 ·2012-09-21 ·Pages 443-4

Ohkura N, Sakaguchi S

Abstract

Foxp3(+) Treg cells express transcription factors normally expressed by specific T helper cells at sites of inflammation. In this issue of Immunity, Koch et al. (2012) and Hall et al. (2012) demonstrate that IFN-γ and IL-27 distinctly induces T-bet(+) Treg cells via STAT-1 transcription factor activation.

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Ohkura Naganari

Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan.

Sakaguchi Shimon

Article Info

Journal

Immunity

Abbr.

Immunity

ISSN

1097-4180

DOI

10.1016/j.immuni.2012.09.004

Published

2012-09-21

Pages

443-4

Language

English

Region

United States

NLM ID

9432918

Corrections

CommentOn

PMID: 22960221

CommentOn

PMID: 22981537

External Links

PubMed source DOI: 10.1016/j.immuni.2012.09.004 View journal details

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