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PMID: 22991088 Published · ppublish English Journal Article

Accessing data from the International Mouse Phenotyping Consortium: state of the art and future plans.

Mammalian genome : official journal of the International Mammalian Genome Society ·Vol. 23 ·No. 9-10 ·2012-10-00 ·Pages 641-52

Mallon AM, Iyer V, Melvin D, Morgan H, Parkinson H, Brown SD, Flicek P, Skarnes WC

Abstract

The International Mouse Phenotyping Consortium (IMPC) (http://www.mousephenotype.org) will reveal the pleiotropic functions of every gene in the mouse genome and uncover the wider role of genetic loci within diverse biological systems. Comprehensive informatics solutions are vital to ensuring that this vast array of data is captured in a standardised manner and made accessible to the scientific community for interrogation and analysis. Here we review the existing EuroPhenome and WTSI phenotype informatics systems and the IKMC portal, and present plans for extending these systems and lessons learned to the development of a robust IMPC informatics infrastructure.

MeSH Terms
Animals Internationality Mice/genetics Phenotype
Authors & Affiliations
8 authors, click to expand affiliations / ORCID
Mallon Ann-Marie
Mammalian Genetics Unit, Medical Research Council Harwell, Harwell, Oxfordshire OX11 0RD, UK. a.mallon@har.mrc.ac.uk
Iyer Vivek
Melvin David
Morgan Hugh
Parkinson Helen
Brown Steve D M
Flicek Paul
Skarnes William C
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Article Info
Journal
Mammalian genome : official journal of the International Mammalian Genome Society
Abbr.
Mamm Genome
ISSN
1432-1777
DOI
10.1007/s00335-012-9428-9
Email
a.mallon@har.mrc.ac.uk
Published
2012-10-00
Epub
2012-00-19
Pages
641-52
Language
English
Region
United States
NLM ID
9100916
PMCID
PMC4106044
Subset
IM
Grants
Medical Research Council · MC_U142684171 · United Kingdom
Medical Research Council · MC_U142684172 · United Kingdom
Medical Research Council · MC_U142684175 · United Kingdom
NHGRI NIH HHS · U54 HG006370 · United States
External Links
PubMed source DOI: 10.1007/s00335-012-9428-9 PMC Full Text View journal details
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