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题目:: Ready, set, go: the EGF receptor at the pancreatic cancer starting line.
作者:: Perera(Rushika M),Bardeesy(Nabeel)
状态:: 发布时间2012-09-14 , 更新时间 2016-10-25
期刊:: Cancer Cell
摘要:: Acinar-to-ductal metaplasia (ADM) results from pancreatic injury or KRAS activation, and is an early step in pancreatic cancer progression. In this issue of Cancer Cell, Ardito and colleagues and Navas and colleagues demonstrate that ADM- and KRAS-driven pancreatic cancer require EGFR signaling, revealing a mechanism for developmental reprogramming that primes tumorigenesis.
语言:: eng
DOI:

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