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PMID: 226547 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Isolation and characterization of the transferrin receptor from human placenta.

The Journal of biological chemistry ·Vol. 254 ·No. 20 ·1979-10-25 ·Pages 9943-6

Seligman PA, Schleicher RB, Allen RH

Abstract

The transferrin receptor has been isolated from human placenta using immunochromatography and affinity chromatography. The receptor is a glycoprotein and has a Mr = 90,000 on sodium dodecyl sulfate-gel electrophoresis in the presence of 2-mercaptoethanol. The isolated receptor is immunologically related to the transferrin receptor on the reticulocyte cell surface.

MeSH Terms
Amino Acids/analysis Carbohydrates/analysis Cell Membrane/metabolism Female Glycoproteins/isolation & purification,metabolism Humans Immunodiffusion Molecular Weight Placenta/metabolism Pregnancy Receptors, Cell Surface/isolation & purification,metabolism Reticulocytes/metabolism Transferrin/metabolism
Chemicals
Amino Acids Carbohydrates Glycoproteins Receptors, Cell Surface Transferrin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Seligman P A
Schleicher R B
Allen R H
Article Info
Journal
The Journal of biological chemistry
Abbr.
J Biol Chem
ISSN
0021-9258
Published
1979-10-25
Pages
9943-6
Language
English
Region
United States
NLM ID
2985121R
Subset
IM
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