Restoring cell polarity: an HSC fountain of youth.
作者:
Carrillo-García(Carmen),Janzen(Viktor)
状态:
发布时间2012-05-07
, 更新时间 2016-05-18
期刊:
Cell Stem Cell
摘要:
Until recently, aging was viewed as a fixed and irreversible process. However, in this issue of Cell Stem Cell, Florian et al. (2012) reveal a link between increased activity of the RhoGTPase Cdc42, hematopoietic stem cell polarity, and aging that can be regulated by pharmacological inhibition of Cdc42.