Method to our madness or madness in our methods? Pitfalls in trial methodology.

Adenocarcinoma/drug therapy Adenocarcinoma of Lung Albumins/administration & dosage Antibodies, Monoclonal/administration & dosage Antineoplastic Combined Chemotherapy Protocols/therapeutic use Carboplatin/administration & dosage Carcinoma, Non-Small-Cell Lung/drug therapy Erlotinib Hydrochloride Female Humans Ipilimumab Lung Neoplasms/drug therapy Male Melanoma/drug therapy Paclitaxel/administration & dosage Quinazolines/administration & dosage Smoking/adverse effects Solvents/chemistry

130-nm albumin-bound paclitaxel Albumins Antibodies, Monoclonal Ipilimumab Quinazolines Solvents Carboplatin Erlotinib Hydrochloride Paclitaxel