Stem-cell-like qualities of immune memory; CD4+ T cells join the party.
作者:
Luckey(C John),Weaver(Casey T)
状态:
发布时间2012-02-06
, 更新时间 2016-10-25
期刊:
Cell Stem Cell
摘要:
Similar to hematopoietic stem cells, memory lymphocytes self-renew, while their clonally expanded effector progeny differentiate to fight infection and tumors. Recently, Muranski et al. (2011) report in Immunity that a subset of Th17 effector cells function as memory cells and retain stem cell properties.