Steps solidifying a role for SEPT9 in breast cancer suggest that greater strides are needed.
作者:
Stanbery(Laura),Petty(Elizabeth M)
状态:
发布时间2012-09-19
, 更新时间 2015-01-28
期刊:
Breast Cancer Res
摘要:
Septins comprise a conserved family of GTPase proteins. Of these, human SEPT9 has been widely implicated in cancers of epithelial origin, including breast cancer, as well as leukemia. In a previous issue of Breast Cancer Research, Connolly and colleagues present compelling data further supporting a role for SEPT9 isoforms in early breast cancer development as well as evidence suggesting that cellular localization patterns of SEPT9 isoforms may contribute to oncogenesis.