| GeneLibs

题目:: GPC5 rs2352028 polymorphism and risk of lung cancer in Han Chinese.
作者:: Zheng(Yonglan),Kan(Mengyuan),Yu(Lan),Niu(Xiaomin),Zhou(Daizhan),He(Lin),Lu(Shun),Liu(Yun)
状态:: 发布时间2012-01-12 , 更新时间 2012-01-12
期刊:: Cancer Invest
摘要:: rs2352028 in GPC5 has been reported to be associated with the risk of lung cancer in never-smokers. We performed a replication study in 1,045 lung cancer patients and 1,094 controls of Han Chinese origin. We found no association between rs2352028 and lung cancer/adenocarcinoma in never-smokers, but a p value of .04 (under the recessive model) was obtained between this SNP and overall lung cancer/adenocarcinoma. Our data and a recent meta-analysis suspected the possibility of rs2352028 being a risk variant of lung cancer risk in never-smokers. Our findings suggested that rs2352028 might confer a slight risk to lung cancer/adenocarcinoma.
语言:: eng
DOI:: 10.3109/07357907.2011.630052

文献库文献相关信息