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题目:: Isolation of adult human pluripotent stem cells from mesenchymal cell populations and their application to liver damages.
作者:: Wakao(Shohei),Kitada(Masaaki),Kuroda(Yasumasa),Dezawa(Mari)
状态:: 发布时间2011-12-14 , 更新时间 2012-11-15
期刊:: Methods Mol Biol
摘要:: We have found a novel type of pluripotent stem cells, Multilineage-differentiating stress enduring (Muse) cells that can be isolated from mesenchymal cell populations. Muse cells are characterized by stress tolerance, expression of pluripotency markers, self-renewal, and the ability to differentiate into endodermal-, mesodermal-, and ectodermal-lineage cells from a single cell, demonstrating that they are pluripotent stem cells. They can be isolated as cells positive for stage-specific embryonic antigen-3, a human pluripotent stem cell marker. Here, we introduce the isolation method for Muse cells and the effect of transplantation of these cells on chronic liver diseases.
语言:: eng
DOI:: 10.1007/978-1-61779-468-1_8

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