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PMID: 219476 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Genetic linkage of C3H/HeJ and BALB/c endogenous ecotropic C-type viruses to phosphoglucomutase-1 on chromosome 5.

Science (New York, N.Y.) ·Vol. 204 ·No. 4388 ·1979-04-06 ·Pages 71-3

Ihle JN, Joseph DR, Domotor JJ

Abstract

The genetic linkage of the endogenous C3H/HeJ C-type ecotropic virus to phosphoglucomutase-1 (0.28, recombinant fraction) on chromosome 5 was established by means of serological assays of backcrossed mice. With a combination of serological techniques and DNA-DNA hybridization the BALB/c endogenous ecotropic virus was shown to be either closely linked or allelic with the C3H/HeJ locus.

MeSH Terms

Alleles Animals Genes Genes, Viral Genetic Linkage Leukemia Virus, Murine/genetics Mice Mice, Inbred BALB C/microbiology Mice, Inbred C3H/microbiology Mice, Inbred Strains/genetics Phenotype Phosphoglucomutase/genetics Retroviridae/genetics

Chemicals

Phosphoglucomutase

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Ihle J N

Joseph D R

Domotor J J

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.219476

Published

1979-04-06

Pages

71-3

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.219476 View journal details

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Genetic linkage of C3H/HeJ and BALB/c endogenous ecotropic C-type viruses to phosphoglucomutase-1 on chromosome 5.

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