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PMID: 2194393 Published · ppublish English Case Reports Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Review

Familial adult T-cell leukemia/lymphoma.

American journal of hematology ·Vol. 34 ·No. 3 ·1990-07-00 ·Pages 215-22

Ratner L, Vander Heyden N, Paine E, Frei-Lahr D, Brown R, Petruska P, Reddy S, Lairmore MD

Abstract

Clinical and laboratory data are described for two siblings who both developed adult T-cell leukemia/lymphoma resulting from infection by human T lymphotropic virus type I (HTLV-I). These findings suggest that genetic factors or virus-specific factors may determine which HTLV-I-infected individuals will develop leukemia.

MeSH Terms

Adult Bone Marrow/pathology Enzyme-Linked Immunosorbent Assay Female HTLV-I Infections/complications Human T-lymphotropic virus 1/isolation & purification Humans Leukemia, T-Cell/etiology,genetics,pathology Lymph Nodes/pathology Lymphoma/etiology,genetics,pathology Male Neoplasms, Multiple Primary/genetics Nucleic Acid Hybridization Polymerase Chain Reaction Radiography Skull/diagnostic imaging

Authors & Affiliations

8 authors, click to expand affiliations / ORCID

Ratner L

Department of Medicine, Washington University, St. Louis, MO 63110.

Vander Heyden N

Paine E

Frei-Lahr D

Brown R

Petruska P

Reddy S

Lairmore M D

Article Info

Journal

American journal of hematology

Abbr.

Am J Hematol

ISSN

0361-8609

DOI

10.1002/ajh.2830340312

Published

1990-07-00

Pages

215-22

Language

English

Region

United States

NLM ID

7610369

Subset

External Links

PubMed source DOI: 10.1002/ajh.2830340312 View journal details

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