Breast cancer in female-to-male transsexuals: two cases with a review of physiology and management.
作者:
Shao(Theresa),Grossbard(Michael L),Klein(Paula)
状态:
发布时间2011-11-28
, 更新时间 2013-11-21
期刊:
Clin Breast Cancer
摘要:
Testosterone is important for the development of secondary sexual characteristics in female-to-male (FtM) transsexuals, but it may increase breast cancer risk. To date, only one breast cancer case has been reported in the literature in a FtM transsexual after 10 years of testosterone therapy. We describe 2 cases of breast cancers diagnosed in FtM transsexuals who have been treated with supraphysiological doses of testosterone. Our 2 cases demonstrate the unique issues that concern the management of FtM transsexuals with breast cancer and examine possible roles of testosterone in the development of breast cancer.