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PMID: 21816342 Published · ppublish English Comment Journal Article

The Ripoptosome: death decision in the cytosol.

Molecular cell ·Vol. 43 ·No. 3 ·2011-08-05 ·Pages 323-5

Bertrand MJ, Vandenabeele P

Abstract

In this issue of Molecular Cell, Tenev et al. and Feoktistova et al. describe the Ripoptosome, a cytosolic death-inducing RIP1-, FADD-, and caspase-8-containing complex that spontaneously assembles upon cIAP depletion, challenging the view that such complexes exclusively originate from receptor activation.

Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Bertrand Mathieu J M
Molecular Signaling and Cell Death Unit, Department for Molecular Biomedical Research, VIB, Ghent, Belgium. mathieu.bertrand@dmbr.vib-ugent.be
Vandenabeele Peter
Article Info
Journal
Molecular cell
Abbr.
Mol Cell
ISSN
1097-4164
DOI
10.1016/j.molcel.2011.07.007
Email
mathieu.bertrand@dmbr.vib-ugent.be
Published
2011-08-05
Pages
323-5
Language
English
Region
United States
NLM ID
9802571
Corrections
CommentOn
PMID: 21737329
CommentOn
PMID: 21737330
External Links
PubMed source DOI: 10.1016/j.molcel.2011.07.007 View journal details
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