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PMID: 217864 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Lipid and lipopolysaccharide composition of Escherichia coli surface-altered mutants selected for resistance to levallorphan, tetracaine, and polymyxin.

Journal of bacteriology ·Vol. 137 ·No. 2 ·1979-02-00 ·Pages 1043-7

Dame JB, Shapiro BM

Abstract

Certain mutants of Escherichia coli with an altered permeability barrier have an essentially normal lipopolysaccharide, fatty acid, and phospholipid content, with a slight increase in the membrane protein:lipid ratio. The phospholipid metabolism of the lev and tec strains shows an abnormal response to growth in the selective agents levallorphan and tetracaine, respectively.

MeSH Terms
Cell Membrane/metabolism Cell Membrane Permeability Drug Resistance, Microbial Escherichia coli/drug effects,genetics,metabolism Levallorphan/pharmacology Lipid Metabolism Lipopolysaccharides/metabolism Membrane Lipids/metabolism Mutation Phospholipids/metabolism Polymyxin B/pharmacology Polymyxins/pharmacology Tetracaine/pharmacology
Chemicals
Lipopolysaccharides Membrane Lipids Phospholipids Polymyxins Tetracaine Levallorphan Polymyxin B
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Dame J B
Shapiro B M
References (16)
16 references, click to expand
  1. RED-CELL AND PLASMA LIPIDS IN ACANTHOCYTOSIS.
    J Clin Invest. 1963 Aug;42:1248-60 PMID: 14060400
  2. A rapid method of total lipid extraction and purification.
    Can J Biochem Physiol. 1959 Aug;37(8):911-7 PMID: 13671378
  3. Phosphorus assay in column chromatography.
    J Biol Chem. 1959 Mar;234(3):466-8 PMID: 13641241
  4. Protein measurement with the Folin phenol reagent.
    J Biol Chem. 1951 Nov;193(1):265-75 PMID: 14907713
  5. Effects of levorphanol on phospholipid metabolism and composition in Escherichia coli.
    Biochim Biophys Acta. 1971 Nov 5;248(2):282-92 PMID: 4943284
  6. [Modifications of phospholipid composition of E. coli cells cultivated in the presence of phenylethanol].
    C R Acad Sci Hebd Seances Acad Sci D. 1970 May 25;270(21):2596-9 PMID: 4987652
  7. Alterations in the outer membrane of the cell envelope of heptose-deficient mutants of Escherichia coli.
    J Bacteriol. 1974 Feb;117(2):527-43 PMID: 4590475
  8. Metabolism and function of the membrane phospholipids of Escherichia coli.
    Biochim Biophys Acta. 1972 Feb 14;265(1):25-60 PMID: 4552305
  9. The identification of trans-2-tetradecenoic acid in hydrolysates of lipid A from Escherichia coli.
    Biochim Biophys Acta. 1972 Jul 7;270(3):289-95 PMID: 4557429
  10. Use of polymyxin B, levallorphan, and tetracaine to isolate novel envelope mutants of Escherichia coli.
    J Bacteriol. 1976 Aug;127(2):961-72 PMID: 182670
  11. Ampicillin-resistant mutants of Escherichia coli K-12 with lipopolysaccharide alterations affecting mating ability and susceptibility to sex-specific bacteriophages.
    J Bacteriol. 1971 Aug;107(2):420-32 PMID: 4939761
  12. Lipids of Salmonella typhimurium and Escherichia coli: structure and metabolism.
    J Bacteriol. 1968 Mar;95(3):833-43 PMID: 4868364
  13. Phospholipid alterations during growth of Escherichia coli.
    J Bacteriol. 1968 Jun;95(6):2054-61 PMID: 4876126
  14. Chemical and biological properties of an extracellular lipopolysaccharide from Escherichia coli grown under lysine-limiting conditions.
    Biochem J. 1966 Apr;99(1):53-61 PMID: 5337757
  15. Characterization of lipopolysaccharides from Escherichia coli K-12 mutants.
    J Bacteriol. 1975 Feb;121(2):455-64 PMID: 1089628
  16. A new method for the extraction of R lipopolysaccharides.
    Eur J Biochem. 1969 Jun;9(2):245-9 PMID: 5804498
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.137.2.1043-1047.1979
Published
1979-02-00
Pages
1043-7
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC218397
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.137.2.1043-1047.1979 PMC Full Text View journal details
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