Rat adipose-tissue glycerol phosphate acyltransferase can be inactivated by cyclic AMP-dependent protein kinase.

The Biochemical journal ·Vol. 176 ·No. 2 ·1978-11-15 ·Pages 607-10

Nimmo HG, Houston B

Abstract

Rat adipose-tissue glycerol phosphate acyltransferase can be inactivated in a phosphorylation reaction catalysed by cyclic AMP-dependent protein kinase and reactivated by treatment with alkaline phosphatase. These results suggest that phosphorylation of glycerol phosphate acyltransferase may be involved in the hormonal control of esterification.

MeSH Terms

Acyltransferases/antagonists & inhibitors Adipose Tissue/enzymology Animals Cyclic AMP/pharmacology Glycerol-3-Phosphate O-Acyltransferase/antagonists & inhibitors In Vitro Techniques Male Microsomes/metabolism Phosphorylation Protein Kinases/pharmacology Rats

Chemicals

Cyclic AMP Acyltransferases Glycerol-3-Phosphate O-Acyltransferase Protein Kinases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Nimmo H G

Houston B

References (25)

25 references, click to expand

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Article Info

Journal

The Biochemical journal

Abbr.

Biochem J

ISSN

0264-6021

DOI

10.1042/bj1760607

Published

1978-11-15

Pages

607-10

Language

English

Region

England

NLM ID

2984726R

PMCID

PMC1186273

Subset

External Links

PubMed source DOI: 10.1042/bj1760607 PMC Full Text View journal details

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Rat adipose-tissue glycerol phosphate acyltransferase can be inactivated by cyclic AMP-dependent protein kinase.

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