Turning reciprocal feedback regulation into combination therapy.
作者:
Thompson(Timothy C)
状态:
发布时间2011-06-13
, 更新时间 2011-08-29
期刊:
Cancer Cell
摘要:
Two recent Cancer Cell articles report the discovery of reciprocal feedback regulation between androgenic and PTEN loss/PI3K-AKT signaling in prostate cancer. Both studies link endocrine regulation with a common oncogenic pathway, which led to the development of a combination therapeutic approach with immediate application in prostate cancer.