Genetic studies on the Gc subtypes.

Human genetics ·Vol. 44 ·No. 2 ·1978-10-31 ·Pages 117-22

Cleve H, Patutschnick W, Nevo S, Wendt GG

Abstract

Gc subtypes were determined by immunofixation isoelectric focusing. In a family study involving 93 families with a total of 176 children, a three-allele model with six genotypes was confirmed. The distribution of Gc subtypes was studied in three populations from Europe and in a sample of Druzes from Northern Israel. Three new variant Gc types were observed.

MeSH Terms

Alleles Carrier Proteins/genetics Child Cholecalciferol/metabolism Gene Frequency Germany Humans Isoelectric Focusing Israel Italy Polymorphism, Genetic

Chemicals

Carrier Proteins Cholecalciferol

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Cleve H

Patutschnick W

Nevo S

Wendt G G

References (4)

4 references, click to expand

Distribution of Gc types in Northern Italy.
Acta Genet Stat Med. 1965;15(3):243-7 PMID: 5899184
Gc subtypes demonstrated by isoelectric focusing: further data and description of new variants among an African sample (Fula) from Senegal.
Jinrui Idengaku Zasshi. 1978 Jun;23(2):111-7 PMID: 691831
Group-specific component: evidence for two subtypes of the Gc1 gene.
Science. 1977 Dec 9;198(4321):1070-1 PMID: 73222
Analysis of the Gc polymorphism in human populations by isoelectrofocusing on polyacrylamide gels. Demonstration of subtypes of the Gc allele and of additional Gc variants.
Hum Genet. 1978 Feb 23;41(1):53-60 PMID: 75833

Article Info

Journal

Human genetics

Abbr.

Hum Genet

ISSN

0340-6717

DOI

10.1007/BF00295404

Published

1978-10-31

Pages

117-22

Language

English

Region

Germany

NLM ID

7613873

Subset

External Links

PubMed source DOI: 10.1007/BF00295404 View journal details

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