Safely modulating the immune system in regenerative medicine.
作者:
Pera(Martin F)
状态:
发布时间2011-03-02
, 更新时间 2016-05-18
期刊:
Cell Stem Cell
摘要:
The destruction of pluripotent stem cell-derived grafts by the host immune system presents a significant barrier to clinical translation of cell therapies. Pearl et al. (2011) report in this issue of Cell Stem Cell that a brief, nontoxic immunosuppressive regimen, achieved by blockade of leucocyte costimulatory pathways, may overcome this problem.