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PMID: 21307931 Published · ppublish English Historical Article Journal Article Review

Initial impact of the sequencing of the human genome.

Nature ·Vol. 470 ·No. 7333 ·2011-02-10 ·Pages 187-97

Lander ES

Abstract

The sequence of the human genome has dramatically accelerated biomedical research. Here I explore its impact, in the decade since its publication, on our understanding of the biological functions encoded in the genome, on the biological basis of inherited diseases and cancer, and on the evolution and history of the human species. I also discuss the road ahead in fulfilling the promise of genomics for medicine.

MeSH Terms
Evolution, Molecular Genetic Predisposition to Disease/genetics Genetics, Medical/trends Genome, Human/genetics History, 21st Century Human Genome Project/history Humans Polymorphism, Genetic/genetics Sequence Analysis, DNA/history
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Lander Eric S
Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA. lander@broadinstitute.org
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Article Info
Journal
Nature
Abbr.
Nature
ISSN
1476-4687
DOI
10.1038/nature09792
Email
lander@broadinstitute.org
Published
2011-02-10
Pages
187-97
Language
English
Region
England
NLM ID
0410462
Subset
IM
Corrections
CommentIn
PMID: 21390116
External Links
PubMed source DOI: 10.1038/nature09792 View journal details
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