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题目:: Molecular targeting of neural cancer stem cells: TTAGGG, you're it!
作者:: Hjelmeland(Anita B),Rich(Jeremy N)
状态:: 发布时间2011-01-06 , 更新时间 2016-11-22
期刊:: Clin Cancer Res
摘要:: Telomerase is an important mechanism by which cancers escape replicative senescence. In neural tumors, cancer stem cells express telomerase, suggesting that this may explain their preferential tumorigenesis. Oligonucleotide telomerase targeting selectively disrupts cancer stem cell growth through the induction of differentiation, adding to the armamentarium of anticancer stem cell therapies.
语言:: eng
DOI:

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