cDNA sequence of a new ras-related gene (rap2b) isolated from human platelets with sequence homology to rap2.

Nucleic acids research ·Vol. 18 ·No. 14 ·1990-07-25 ·Pages 4281

Farrell FX, Ohmstede CA, Reep BR, Lapetina EG

Abstract

暂无摘要

MeSH Terms

Amino Acid Sequence Base Sequence Blood Platelets/metabolism DNA/genetics GTP-Binding Proteins/genetics Genes, ras Humans Molecular Sequence Data Sequence Homology, Nucleic Acid

Chemicals

DNA GTP-Binding Proteins

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Farrell F X

Division of Cell Biology, Burroughs Wellcome Co., Research Triangle Park, NC 27709.

Ohmstede C A

Reep B R

Lapetina E G

References (5)

5 references, click to expand

ras p21 deletion mutants and monoclonal antibodies as tools for localization of regions relevant to p21 function.
Proc Natl Acad Sci U S A. 1986 Aug;83(15):5400-4 PMID: 2426696
Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region.
Oncogene. 1988 Aug;3(2):201-4 PMID: 3045729
Thrombolamban, the 22-kDa platelet substrate of cyclic AMP-dependent protein kinase, is immunologically homologous with the Ras family of GTP-binding proteins.
Proc Natl Acad Sci U S A. 1990 Jan;87(2):758-62 PMID: 1689052
Agonist-induced phosphorylation of an immunologically ras-related protein in human erythroleukemia cells.
Biochem Biophys Res Commun. 1989 Jun 30;161(3):972-8 PMID: 2472791
A ras-related protein is phosphorylated and translocated by agonists that increase cAMP levels in human platelets.
Proc Natl Acad Sci U S A. 1989 May;86(9):3131-4 PMID: 2470091

Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

DOI

10.1093/nar/18.14.4281

Published

1990-07-25

Pages

4281

Language

English

Region

England

NLM ID

0411011

PMCID

PMC331220

Subset

Databases

GENBANK

X52987

External Links

PubMed source DOI: 10.1093/nar/18.14.4281 PMC Full Text View journal details

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cDNA sequence of a new ras-related gene (rap2b) isolated from human platelets with sequence homology to rap2.

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